{"id":8733,"date":"2023-04-05T09:25:53","date_gmt":"2023-04-05T09:25:53","guid":{"rendered":"https:\/\/organonpro.com\/kr-kr\/?page_id=8733"},"modified":"2026-09-10T02:06:18","modified_gmt":"2026-09-10T02:06:18","slug":"atozet_ssi","status":"publish","type":"page","link":"https:\/\/organonpro.com\/ko-kr\/atozet_ssi\/","title":{"rendered":"Atozet Selected Safety Information"},"content":{"rendered":"\n

\uc544\ud1a0\uc82f \uc815 <\/strong>(\uc5d0\uc81c\ud2f0\ubbf8\ube0c\/\uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4) 10\/10, 10\/20, 10\/40, 10\/80 mg<\/strong><\/h2>\n\n\n\n

[\ud6a8\ub2a5\u00b7\ud6a8\uacfc]<\/strong><\/p>\n\n\n\n

\uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(\uc774\ud615\uc811\ud569 \uac00\uc871\ud615 \ubc0f \ube44\uac00\uc871\ud615) \ub610\ub294 \ud63c\ud569\ud615 \uc774\uc0c1\uc9c0\uc9c8\ud608\uc99d \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d \ucf5c\ub808\uc2a4\ud14c\ub864(total-C), LDL-\ucf5c\ub808\uc2a4\ud14c\ub864(LDL-C), \uc544\ud3ec B \ub2e8\ubc31(Apo B) \ubc0f \ud2b8\ub9ac\uae00\ub9ac\uc138\ub77c\uc774\ub4dc(TG) \ubc0f non-HDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0, HDL-\ucf5c\ub808\uc2a4\ud14c\ub864(HDL-C)\uc744 \uc99d\uac00\uc2dc\ud0a4\uae30 \uc704\ud55c \uc2dd\uc774\uc694\ubc95\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c \ud22c\uc5ec\ud55c\ub2e4. \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(HoFH) \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d\ucf5c\ub808\uc2a4\ud14c\ub864 \ubc0f LDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc744 \uac10\uc18c\uc2dc\ud0a4\uae30 \uc704\ud55c \ub2e4\ub978 \uc9c0\uc9c8\uc800\ud558 \uce58\ub8cc(\uc608, LDL-Apheresis)\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c, \ub610\ub294 \ub2e4\ub978 \uc9c0\uc9c8 \uc800\ud558 \uce58\ub8cc\uac00 \uc720\uc6a9\ud558\uc9c0 \uc54a\uc740 \uacbd\uc6b0 \ud22c\uc5ec\ud55c\ub2e4.<\/p>\n\n\n\n

[\uc6a9\ubc95\u00b7\uc6a9\ub7c9]<\/strong><\/p>\n\n\n\n

\uc774 \uc57d\uc740 \uc2dd\uc0ac\uc640 \uad00\uacc4\uc5c6\uc774 1\uc77c 1\ud68c \ud22c\uc5ec\ud55c\ub2e4. \uc774 \uc57d\uc744 \ud22c\uc5ec\ud558\uae30 \uc804 \ub610\ub294 \ud22c\uc5ec \uc911\uc778 \ud658\uc790\ub294 \ubc18\ub4dc\uc2dc \ud45c\uc900 \ucf5c\ub808\uc2a4\ud14c\ub864 \uc800\ud558\uc2dd\uc744 \uc9c0\uc18d\uc801\uc73c\ub85c \ud574\uc57c \ud55c\ub2e4. \uc774 \uc57d\uc758 \ud22c\uc5ec\ub7c9\uc740 \ud658\uc790\uc758 LDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc758 \uae30\uc800\uce58, \uad8c\uc7a5\ub418\ub294 \uce58\ub8cc \ubaa9\ud45c\uce58 \ubc0f \ud658\uc790\uc758 \ubc18\uc751\uc5d0 \ub530\ub77c \uc870\uc808\ub418\uc5b4\uc57c \ud55c\ub2e4. \uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d \uc774 \uc57d\uc758 \uc6a9\ub7c9 \ubc94\uc704\ub294 1\uc77c 10\/10 mg\u223c10\/80 mg\uc774\ub2e4. \ucd08\ud68c \uc6a9\ub7c9\uc73c\ub85c 1\uc77c 10\/10 mg  \ub610\ub294 10\/20 mg\uc774 \uad8c\uc7a5\ub41c\ub2e4. LDL-\ucf5c\ub808\uc2a4\ud14c\ub864 \uac10\uc18c\uac00 \ub354 \ub9ce\uc774(55% \uc774\uc0c1) \uc694\uad6c\ub418\ub294 \ud658\uc790\uc758 \uacbd\uc6b0, \ucd08\ud68c \uc6a9\ub7c9\uc73c\ub85c 1\uc77c 10\/40 mg\uc774 \uad8c\uc7a5 \ub41c\ub2e4. \uc774 \uc57d\uc758 \ud22c\uc5ec\ub97c \uc2dc\uc791\ud55c \ud6c4 \ub610\ub294 \uc6a9\ub7c9\uc744 \uc801\uc815\ud55c \ud6c4\uc5d0\ub294 2\uc8fc \uc774\uc0c1\uc758 \uac04\uaca9\uc744 \ub450\uace0 \ud608\uc911 \uc9c0\uc9c8 \uc218\uce58\ub97c \ud655\uc778\ud55c \ud6c4 \uadf8\uc5d0 \ub530\ub77c \uc6a9\ub7c9\uc744 \uc870\uc808\ud55c\ub2e4. \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d \ud658\uc790\uc758 \uad8c\uc7a5 \uc6a9\ub7c9\uc740 1\uc77c 10\/40 mg \ub610\ub29410\/80 mg\uc774\ub2e4. \uc774 \uc57d\uc740 \ub2e4\ub978 \uc9c0\uc9c8 \uc800\ud558\uce58\ub8cc(\uc608, LDL-Apheresis)\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c \ub610\ub294 \ub2e4\ub978 \uc9c0\uc9c8 \uc800\ud558 \uce58\ub8cc\uac00 \uc720\uc6a9\ud558\uc9c0 \uc54a\ub294 \uacbd\uc6b0 \ud22c\uc5ec\ud55c\ub2e4. .<\/p>\n\n\n\n

[\uc0ac\uc6a9\uc0c1\uc758 \uc8fc\uc758\uc0ac\ud56d] <\/strong><\/p>\n\n\n\n

[\uae08\uae30]<\/strong><\/p>\n\n\n\n

\uc544\ud1a0\uc82f\uc815\uc758 \uc8fc\uc131\ubd84 \ub610\ub294 \uad6c\uc131\uc131\ubd84\uc5d0 \uacfc\ubbfc\uc99d\uc778 \ud658\uc790, \ud65c\ub3d9\uc131 \uac04\uc9c8\ud658 \ud658\uc790 \ub610\ub294 \ud608\uccad \uc544\ubbf8\ub178\uc804\uc774\ud6a8\uc18c \uc218\uce58\uac00 \uc6d0\uc778\ubd88\uba85\uc73c\ub85c \uc9c0\uc18d\uc801\uc73c\ub85c \ub192\uc740 \uc99d\uc0c1\uc744 \uc218\ubc18\ud55c \ud658\uc790(\u20185. \uc77c\ubc18\uc801 \uc8fc\uc758\u2019 \ucc38\uc870), \uadfc\uc9c8\ud658 \ud658\uc790, \uc784\ubd80 \ub610\ub294 \uc784\uc2e0\ud558\uace0 \uc788\uc744 \uac00\ub2a5\uc131\uc774 \uc788\ub294 \uc5ec\uc131 \ubc0f \uc218\uc720\ubd80(\u20187. \uc784\ubd80 \ubc0f \uc218\uc720\ubd80\uc5d0 \ub300\ud55c \ud22c\uc5ec\u2019 \ucc38\uc870),  \uae00\ub808\uce74\ud504\ub808\ube44\ub974 \ubc0f \ud53c\ube0c\ub80c\ud0c0\uc2a4\ube44\ub974\ub97c \ud22c\uc5ec \uc911\uc778 \ud658\uc790, \uc774 \uc57d\uc740 \uc720\ub2f9\uc744 \ud568\uc720\ud558\uace0 \uc788\uc73c\ubbc0\ub85c, \uac08\ub77d\ud1a0\uc624\uc2a4 \ubd88\ub0b4\uc131(galactose intolerance), Lapp \uc720\ub2f9\ubd84\ud574\ud6a8\uc18c \uacb0\ud54d\uc99d(Lapp lactase deficiency) \ub610\ub294 \ud3ec\ub3c4\ub2f9- \uac08\ub77d\ud1a0\uc624\uc2a4 \ud761\uc218 \uc7a5\uc560(glucose-galactose malabsorption)\ub4f1\uc758 \uc720\uc804\uc801\uc778 \ubb38\uc81c\uac00 \uc788\ub294 \ud658\uc790<\/p>\n\n\n\n

[\uacbd\uace0]<\/strong><\/p>\n\n\n\n

1) \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4 \ubc0f \ub3d9\uc77c  \uacc4\uc5f4\uc758  \ub2e4\ub978  \uc57d\ubb3c\uc5d0\uc11c  \ubbf8\uc624\uae00\ub85c\ube48\ub1e8\uc5d0  \uc758\ud55c  \uc774\ucc28\uc801\uc778 \uae09\uc131 \uc2e0\ubd80\uc804\uc744 \ub3d9\ubc18\ud558\ub294 \ud6a1\ubb38\uadfc\uc735\ud574\uac00 \ub4dc\ubb3c\uac8c \ubcf4\uace0\ub418\uc5c8\ub2e4. \ub530\ub77c\uc11c \uae09\uc131\uc758 \uc2ec\uac01\ud55c \uadfc\uc721\ubcd1\uc99d\uc744 \ub098\ud0c0\ub0b4\ub294 \ud658\uc790 \ub610\ub294  \ud6a1\ubb38\uadfc\uc735\ud574\uc5d0  \uc758\ud574  \uc774\ucc28\uc801\uc73c\ub85c  \uc2e0\ubd80\uc804\uc774  \ubc1c\uc0dd\ub420  \uc218 \uc788\ub294 \uc704\ud5d8\uc694\uc18c(\uc608, \uc911\uc99d \uae09\uc131 \uac10\uc5fc, \uc800\ud608\uc555, \uc8fc\uc694 \uc678\uacfc\uc218\uc220, \uc678\uc0c1, \uc911\uc99d\uc758 \ub300\uc0ac, \ub0b4\ubd84\ube44 \ubc0f \uc804\ud574\uc9c8 \uc7a5\uc560, \uc870\uc808\ub418\uc9c0 \uc54a\ub294 \ubc1c\uc791)\ub97c \uac00\uc9c4 \ud658\uc790\ub294 \uc774  \uc57d\uc758  \uce58\ub8cc\ub97c \uc77c\uc2dc\uc801\uc73c\ub85c \ubcf4\ub958\ud558\uac70\ub098 \ub610\ub294 \uc911\ub2e8\ud574\uc57c \ud55c\ub2e4(\u20185. \uc77c\ubc18\uc801 \uc8fc\uc758\u2019 \ucc38\uc870).<\/p>\n\n\n\n

[\uc2e0\uc911\ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

1) \uc54c\ucf54\uc62c \uc911\ub3c5\uc790 \ub610\ub294 \uac04\uc9c8\ud658\uc758 \ubcd1\ub825\uc774 \uc788\ub294 \ud658\uc790 2) \uc911\ub4f1\uc99d \ub610\ub294 \uc911\uc99d\uc758 \uac04\uae30\ub2a5 \uc7a5\uc560 \ud658\uc790 3) \ub2e4\uc74c\uacfc \uac19\uc740 \uadfc\uc721\ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574\uc5d0 \uac78\ub9ac\uae30 \uc26c\uc6b4 \uc694\uc778\uc744 \uac00\uc9c4 \ud658\uc790 (1) \uc2e0\uae30\ub2a5 \uc190\uc0c1 \ub610\ub294 \uc2e0\uc7a5\uc560 \ubcd1\ub825 (2) \uac11\uc0c1\uc120\uae30\ub2a5\uc800\ud558\uc99d(3) \uc720\uc804\uc801\uc778 \uadfc\uc9c8\ud658 \ubcd1\ub825 \ub610\ub294 \uac00\uc871\ub825 (4) \uc2a4\ud0c0\ud2f4 \uacc4\uc5f4 \ub610\ub294 \ud53c\ube0c\ub808\uc774\ud2b8 \uacc4\uc5f4 \uc57d\ubb3c\uc5d0 \ub300\ud55c \uadfc\uc721 \ub3c5\uc131\uc758 \ubcd1\ub825 (5) \uac04\uc9c8\ud658\uc758 \ubcd1\ub825 \ub610\ub294 \uc0c1\ub2f9\ub7c9\uc758 \uc54c\ucf54\uc62c\uc744 \uc12d\ucde8\ud558\ub294 \uacbd\uc6b0 (6) 70\uc138\ub97c \ucd08\uacfc\ud558\ub294 \uace0\ub839\uc790\ub85c \ud6a1\ubb38\uadfc\uc735\ud574\uc758 \uc694\uc778\uc744 \uac00\uc9c4 \uacbd\uc6b0 (7) \ud608\uc911 \uc57d\ubb3c \ub18d\ub3c4\uac00 \uc99d\uac00\ud560 \uc218 \uc788\ub294 \uacbd\uc6b0 4)\ud53c\ube0c\ub808\uc774\ud2b8 \uacc4\uc5f4 \uc57d\ubb3c\uc744 \ubcd1\uc6a9\ud22c\uc5ec\ud558\ub294 \ud658\uc790 5) \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d \ub610\ub294 \uc548\uadfc \ubb34\ub825\uc99d \ud658\uc790(\uac19\uc740 \uc885\ub958 \ub610\ub294 \ub2e4\ub978 \uc885\ub958\uc758 \uc2a4\ud0c0\ud2f4\uacc4 \uc57d\ubb3c\uc744 \ud22c\uc5ec\ud588\uc744 \ub54c \uc7ac\ubc1c\ud55c \uc0ac\ub840\uac00 \ubcf4\uace0\ub418\uc5c8\ub2e4.<\/p>\n\n\n\n

[\uc774\uc0c1\ubc18\uc751]<\/strong><\/p>\n\n\n\n

\uc544\ud1a0\uc82f\uc815(\uc5d0\uc81c\ud2f0\ubbf8\ube0c\uc640 \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4)\uc5d0 \ub300\ud55c \uc704\uc57d \ub300\uc870 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \ud22c\uc5ec \uae30\uac04\uc758 \uc911\uc559\uac12\uc740 12\uc8fc\uc600\uc73c\uba70 628\uba85\uc758 \ud658\uc790(\uc5f0\ub839 \ubc94\uc704: \ub9cc 18-86\uc138, \uc5ec\uc131: 59%, \ucf54\uce74\uc2dc\uc548: 85%, \ud751\uc778: 6%, \ud788\uc2a4\ud328\ub2c9: 5%, \uc544\uc2dc\uc544\uc778: 3%) \uc911 \uc774\uc0c1\ubc18\uc751\uc73c\ub85c \ud22c\uc5ec\ub97c \uc911\ub2e8\ud55c \ud658\uc790\ub294 \uc774 \uc57d \ud22c\uc5ec\uad70\uc5d0\uc11c 6%, \uc704\uc57d \ud22c\uc5ec\uad70\uc5d0\uc11c 5%\uc600\ub2e4. \uc704\uc57d\uad70\ubcf4\ub2e4 \uc774 \uc57d \ud22c\uc5ec\uad70\uc5d0\uc11c \ub192\uc740 \ube44\uc728\ub85c \ubc1c\uc0dd\ud558\uc5ec \uc57d\ubb3c \ud22c\uc5ec \uc911\ub2e8\uc758 \uc6d0\uc778\uc774 \ub41c \uac00\uc7a5 \ud754\ud55c \uc774\uc0c1\ubc18\uc751\uc740 \uadfc\uc721\ud1b5(0.8%), \ubcf5\ud1b5(0.8%), \uac04 \ud6a8\uc18c \uc0c1\uc2b9(0.8%)\uc774\uc5c8\uc73c\uba70, \uac00\uc7a5 \ud754\ud558\uac8c \ubcf4\uace0\ub41c \uc774\uc0c1\ubc18\uc751\uc740 ALT \uc99d\uac00(5%), AST \uc99d\uac00(4%), \uadfc \uace8\uaca9\uacc4 \ud1b5\uc99d(4%)\uc774\uc5c8\ub2e4. \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4\uc5d0\uc11c \uc218\uc9d1\ub41c \uc815\ubcf4\uc758 \uadfc \uace8\uaca9\uacc4 \ubc0f \uacb0\ud569\uc870\uc9c1\uc5d0\uc11c \uadfc\uc721 \ud30c\uc5f4, \ub9e4\uc6b0 \ub4dc\ubb3c\uac8c \ub8e8\ud478\uc2a4\uc591 \uc99d\ud6c4\uad70\uc774 \ucd94\uac00 \ubcf4\uace0\ub418\uc5c8\ub2e4. \uad6d\ub0b4\uc5d0\uc11c \uc2dc\ud310 \ud6c4 (1) \ud608\uad00\uacc4 : \ud608\uad00\uc5fc (2) \ud53c\ubd80 \ubc0f \ud53c\ud558\uc870\uc9c1 : \ud0dc\uc120 \ubaa8\uc591 \uc57d\ubb3c \ubc18\uc751\uc774 \ucd94\uac00\ub85c \ubcf4\uace0\ub418\uc5c8\ub2e4. \uc77c\ubd80 \uc2a4\ud0c0\ud2f4\uacc4 \uc57d\ubb3c \ud22c\uc5ec\uc640 \uad00\ub828\ud558\uc5ec \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d \ub610\ub294 \uc548\uadfc \ubb34\ub825\uc99d\uc758 \uc720\ubc1c \ub610\ub294 \uc545\ud654\uac00 \ubcf4\uace0\ub418\uc5c8\ub2e4 (\u20183. \ub2e4\uc74c \ud658\uc790\uc5d0\ub294 \uc2e0\uc911\ud788 \ud22c\uc5ec\ud560 \uac83\u2019\ud56d \ubc0f \u20185. \uc77c\ubc18\uc801 \uc8fc\uc758 2) \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d\/\uc548\uadfc \ubb34\ub825\uc99d\u2019\ud56d \ucc38\uc870).<\/p>\n\n\n\n

[\uc77c\ubc18\uc801 \uc8fc\uc758]<\/strong><\/p>\n\n\n\n

1) \uadfc\uc721\ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574 \uadfc\uc721\ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574\uc5d0 \uac78\ub9ac\uae30 \uc26c\uc6b4 \uc694\uc778\uc744 \uac00\uc9c4  \ud658\uc790(\u20183. \ub2e4\uc74c \ud658\uc790\uc5d0\ub294 \uc2e0\uc911\ud788  \ud22c\uc5ec\ud560 \uac83\u2019 \ud56d \ucc38\uc870)\uc758 \uacbd\uc6b0, \ud22c\uc5ec\ub97c \uc2dc\uc791\ud558\uae30 \uc804\uc5d0 CPK \uc218\uce58\ub97c \uce21\uc815\ud558\uc5ec \uc2e0\uc911\ud788 \ud22c\uc5ec\ud574\uc57c \ud55c\ub2e4. \uc774\ub7ec\ud55c \ud658\uc790\ub4e4\uc5d0\uc11c \uce58\ub8cc\uc758 \uc704\ud574\uc131\uc740 \uc720\uc775\uc131\uacfc \ud568\uaed8 \uace0\ub824\ub418\uc5b4\uc57c \ud558\uba70 \uc784\uc0c1\uc801 \ubaa8\ub2c8\ud130\ub9c1\uc774 \uad8c\uc7a5\ub41c\ub2e4. \ub2f5\ud1a0\ub9c8\uc774\uc2e0\uacfc HMG-CoA \ud658\uc6d0 \uc694\uc18c \uc5b5\uc81c\uc81c\ub97c \ubcd1\uc6a9\ud22c\uc5ec\ud558\uc600\uc744 \ub54c \uadfc\uc721\ubcd1\uc99d \ubc0f\/\ub610\ub294 \ud6a1\ubb38\uadfc\uc735\ud574\uac00 \ubcf4\uace0\ub418\uc5c8\ub2e4. \ub2f5\ud1a0\ub9c8\uc774\uc2e0 \ubc0f HMG-CoA \ud658\uc6d0 \ud6a8\uc18c \uc5b5\uc81c\uc81c \uac01\uac01 \ub2e8\ub3c5 \ud22c\uc5ec \uc2dc \uadfc\uc721\ubcd1\uc99d \ubc0f\/\ub610\ub294 \ud6a1\ubb38\uadfc\uc735\ud574\uac00 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc73c\ubbc0\ub85c \ubcd1\uc6a9\ud22c\uc5ec \uc2dc \uc8fc\uc758\ub97c \uae30\uc6b8\uc5ec\uc57c \ud55c\ub2e4. \ub2f5\ud1a0\ub9c8\uc774\uc2e0\uc744 \ud22c\uc5ec \uc911\uc778 \ud658\uc790\uc5d0\uc11c \uc77c\uc2dc\uc801\uc73c\ub85c \uc774 \uc57d\uc758 \ud22c\uc5ec\ub97c \uc911\ub2e8\ud558\ub294 \uac83\uc744 \uace0\ub824\ud574\uc57c \ud55c\ub2e4 (\u20186. \uc0c1\ud638\uc791\uc6a9\u2019 \ud56d \ucc38\uc870) 2) \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d\/\uc548\uadfc \ubb34\ub825\uc99d \ub4dc\ubb3c\uac8c \uc2a4\ud0c0\ud2f4\uacc4 \uc57d\ubb3c\uc774 \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d \ub610\ub294 \uc548\uadfc \ubb34\ub825\uc99d\uc744 \uc720\ubc1c\ud558\uac70\ub098 \uc545\ud654\uc2dc\ud0ac \uc218 \uc788\ub2e4(\u20184. \uc774\uc0c1\ubc18\uc751\u2019\ud56d \ucc38\uc870). \uc774 \uc57d\uc740 \uc774\ub7ec\ud55c \uc0c1\ud0dc\uc758 \ud658\uc790\uc5d0\uac8c \uc8fc\uc758\ud574\uc11c \uc0ac\uc6a9\ud574\uc57c \ud55c\ub2e4. (\u20183. \ub2e4\uc74c \ud658\uc790\uc5d0\ub294 \uc2e0\uc911\ud788 \ud22c\uc5ec\ud560 \uac83\u2019\ud56d \ucc38\uc870). \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d \ub610\ub294 \uc548\uadfc \ubb34\ub825\uc99d\uc774 \uc720\ubc1c\ub418\uac70\ub098 \uc545\ud654\ub41c \uacbd\uc6b0 \ud22c\uc5ec\ub97c \uc911\ub2e8\ud574\uc57c\ud55c\ub2e4. 3) \uac04\ud6a8\uc18c \uc774 \uc57d \ud22c\uc5ec \uc2dc\uc791 \uc804\uc5d0 \uac04 \ud6a8\uc18c \uac80\uc0ac\ub97c \uc2e4\uc2dc\ud574\uc57c \ud558\uace0 \uc784\uc0c1\uc801\uc73c\ub85c \uac04 \uc190\uc0c1\uc758 \uc9d5\ud6c4 \ub610\ub294 \uc99d\uc0c1\uc774 \ub098\ud0c0\ub098\ub294 \ud658\uc790\uc758 \uacbd\uc6b0, \uac04\uae30\ub2a5 \uac80\uc0ac\ub97c \ubc18\ubcf5\ud574\uc57c \ud55c\ub2e4. \ud2b8\ub79c\uc2a4\uc544\ubbf8\ub098\uc81c\uac00 \uc0c1\uc2b9\ud55c \ud658\uc790\ub4e4\uc758 \uacbd\uc6b0, \uc774\uc0c1 \uc99d\uc0c1\uc774 \uac1c\uc120\ub420 \ub54c\uae4c\uc9c0 \ubaa8\ub2c8\ud130\ub9c1\ud574\uc57c \ud55c\ub2e4. \ud2b8\ub79c\uc2a4\uc544\ubbf8\ub098\uc81c\uac00 \uc815\uc0c1\uc0c1\ud55c\uce58\uc758 3\ubc30 \uc774\uc0c1 \uc9c0\uc18d\uc801\uc73c\ub85c \uc99d\uac00\ud558\ub294 \uacbd\uc6b0, \uc774 \uc57d\uc758 \uc6a9\ub7c9\uc744 \uac10\ub7c9\ud558\uac70\ub098 \ud22c\uc5ec\ub97c \uc911\ub2e8\ud560 \uac83\uc744 \uad8c\uc7a5\ud55c\ub2e4. \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4\uc744 \ud3ec\ud568\ud558\uc5ec \uc2a4\ud0c0\ud2f4\uc744 \ubcf5\uc6a9\ud55c \ud658\uc790\uc5d0\uc11c\uc758 \uc2dc\ud310 \ud6c4 \uc870\uc0ac \uacb0\uacfc, \uce58\uba85\uc801 \uadf8\ub9ac\uace0 \ube44\uce58\uba85\uc801 \uac04\ubd80\uc804\uc774 \ub4dc\ubb3c\uac8c \ubcf4\uace0\ub418\uc5c8\ub2e4. \uc774 \uc57d\uc73c\ub85c \uce58\ub8cc\ud558\ub294 \ub3d9\uc548 \uc784\uc0c1\uc801 \uc99d\uc0c1\uacfc \ud568\uaed8 \uc911\uc99d\uc758 \uac04 \uc190\uc0c1 \uadf8\ub9ac\uace0\/\ub610\ub294 \uace0\ube4c \ub9ac\ub8e8\ube48\ud608\uc99d \ub610\ub294 \ud669\ub2ec\uc774 \ubc1c\uc0dd\ud55c \uacbd\uc6b0, \uc989\uc2dc \uc774 \uc57d\uc758 \uce58\ub8cc\ub97c \uc911\ub2e8\ud55c\ub2e4. \ub2e4\ub978 \ubcd1\uc778\uc774 \ud655\uc778\ub418\uc9c0 \uc54a\uc744 \uacbd\uc6b0, \uc774 \uc57d\uc744 \uc7ac\ud22c\uc5ec\ud558\uc9c0 \uc54a\ub294\ub2e4. \uc774 \uc57d\uc744 \uc54c\ucf54\uc62c \uacfc\ub2e4 \ubcf5\uc6a9 \ud658\uc790 \uadf8\ub9ac\uace0\/\ub610\ub294 \uac04\uc9c8\ud658\uc758 \ubcd1\ub825\uc774 \uc788\ub294 \ud658\uc790\uc5d0\uac8c \ud22c\uc5ec \uc2dc \uc8fc\uc758\ud574\uc57c \ud55c\ub2e4. \ud65c\uc131 \uac04\uc9c8\ud658 \ub610\ub294 \uc6d0\uc778\uc774 \ubc1d\ud600\uc9c0\uc9c0 \uc54a\ub294 \ud608\uccad \ud2b8\ub79c\uc2a4\uc544\ubbf8\ub098\uc81c\uc758 \uc9c0\uc18d\uc801 \uc0c1\uc2b9\uc774 \uc788\ub294 \ud658\uc790\uc5d0\uac8c\ub294 \uc774 \uc57d\uc744 \ud22c\uc5ec\ud558\uc9c0 \uc54a\ub294\ub2e4.(\u20182. \ub2e4\uc74c \ud658\uc790\uc5d0\ub294 \ud22c\uc5ec\ud558\uc9c0 \ub9d0 \uac83\u2019 \ud56d \ucc38\uc870)<\/p>\n\n\n\n

[\uc0c1\ud638\uc791\uc6a9]<\/strong> <\/p>\n\n\n\n

\uc774 \uc57d\uc758 \uc8fc\uc131\ubd84\uc778 \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4\uacfc \uc5d0\uc81c\ud2f0\ubbf8\ube0c \ubcd1\uc6a9\ud22c\uc5ec \uc2dc \uc784\uc0c1\uc801\uc73c\ub85c \uc720\uc758\ud55c \uc57d\ub3d9\ud559\uc801 \uc0c1\ud638\uc791\uc6a9\uc740 \ub098\ud0c0\ub098\uc9c0 \uc54a\uc558\ub2e4. \uc774 \uc57d\uc758 \uc8fc\uc131\ubd84\uc778 \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4\uc740 CYP3A4\uc5d0 \uc758\ud574 \ub300\uc0ac \ub418\uba70 \uac04 \ud761\uc218 \uc57d\ubb3c\uc218\uc1a1\uccb4\uc778 OATP1B1\uacfc \uac19\uc740 \uc218\uc1a1\uccb4 \ub2e8\ubc31\uc9c8\uc758 \uae30\uc9c8\uc774\ub2e4. \uadf8\ub7ec\ubbc0\ub85c \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4\uacfc CYP3A4 \uc800\ud574\uc81c \ub610\ub294 \uc218\uc1a1\uccb4 \ub2e8\ubc31\uc9c8 \uc5b5\uc81c\uc81c \ubcd1\uc6a9\ud22c\uc5ec \uc2dc \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4\uc758 \ud608\uc7a5\ub18d\ub3c4 \ubc0f \uadfc\uc721 \ubcd1\uc99d\uc758 \uc704\ud5d8\uc774 \uc99d\uac00\ud560 \uc218 \uc788\ub2e4. \ub530\ub77c\uc11c \ud53c\ube0c\ub9ad\uc0b0 \uc720\ub3c4\uccb4 \ub610\ub294 \uc5d0\uc81c\ud2f0\ubbf8\ube0c\uc640 \uac19\uc774 \uadfc\uc721\ubcd1\uc99d\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\ub294 \uc57d\ubb3c\uacfc \uc774 \uc57d\uc744 \ubcd1\uc6a9\ud22c\uc5ec \ud558\ub294 \uacbd\uc6b0\uc5d0\ub3c4 \uc774\ub7ec\ud55c \uc704\ud5d8\uc774 \uc99d\uac00\ud560 \uc218 \uc788\ub2e4.<\/p>\n\n\n\n

[\uc784\ubd80 \ubc0f \uc218\uc720\ubd80\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

1) \ub3d9\ub9e5\uacbd\ud654\uc99d\uc740 \ub9cc\uc131\uc9c8\ud658\uc774\uba70, \uc784\uc2e0 \uc911 \uc9c0\uc9c8\uc800\ud558\uc81c \ud22c\uc5ec\ub97c \uc911\uc9c0\ud574\ub3c4 \uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d\uc758 \uc7a5\uae30 \uce58\ub8cc \uacb0\uacfc\uc5d0 \uc601\ud5a5\uc744 \uc8fc\uc9c0 \uc54a\ub294\ub2e4. \ub610\ud55c \ucf5c\ub808\uc2a4\ud14c\ub864\uacfc \ucf5c\ub808\uc2a4\ud14c\ub864 \uc0dd\ud569\uc131 \uacbd\ub85c\uc758 \ub2e4\ub978 \uc0dd\uc131\ubb3c\uc740 \uc2a4\ud14c\ub85c\uc774\ub4dc, \uc138\ud3ec\ub9c9 \ud569\uc131 \ub4f1\uc758 \ud0dc\uc544 \ubc1c\ub2ec\uc5d0 \ud544\uc218\uc801\uc778 \uc131\ubd84\uc774\ub2e4. \uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4\uc744 \ud3ec\ud568\ud55c HMG-CoA \ud658\uc6d0\ud6a8\uc18c\uc800\ud574\uc81c\uac00 \ucf5c\ub808\uc2a4\ud14c\ub864 \ud569\uc131 \ubc0f \ucf5c\ub808\uc2a4\ud14c\ub864 \uc0dd\ud569\uc131\uacbd\ub85c\uc758 \ub2e4\ub978 \uc0dd\uc131\ubb3c\uc744 \uac10\uc18c\uc2dc\ud0ac \uc6b0\ub824\uac00 \uc788\uc73c\ubbc0\ub85c \uc784\ubd80 \ub610\ub294 \uc218\uc720\ubd80\uc5d0\uac8c \uc774 \uc57d\uc744 \ud22c\uc5ec\ud574\uc11c\ub294 \uc548\ub41c\ub2e4. \uc784\ubd80\uc5d0 \ub300\ud55c \uc774 \uc57d\uc758  \uc548\uc804\uc131\uc740  \ud655\ub9bd\ub418\uc5b4 \uc788\uc9c0 \uc54a\uae30 \ub54c\ubb38\uc5d0 \uc784\uc2e0\uc774 \ud655\uc778\ub418\uba74 \uc989\uc2dc \ud22c\uc5ec\ub97c \uc911\uc9c0\ud558\uace0 \ud658\uc790\uc5d0\uac8c \ud0dc\uc544\uc5d0 \ub300\ud55c \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc131\uc744 \uc54c\ub824\uc57c \ud55c\ub2e4. \uac00\uc784 \uc5ec\uc131\uc5d0\uac8c\ub294 \uc784\uc2e0 \uac00\ub2a5\uc131\uc774 \uac70\uc758 \uc5c6\ub294 \uacbd\uc6b0, \ud0dc\uc544\uc5d0 \ubbf8\uce60 \uc218 \uc788\ub294 \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc131 \ubc0f \uc784\uc2e0 \uc911 \ud22c\uc5ec\ub97c \uc9c0\uc18d\ud558\uc5ec\ub3c4 \uc784\uc0c1\uc801 \uc720\uc775\uc131\uc774 \uc5c6\ub2e4\ub294 \uc810\uc744  \uc54c\ub824\uc900 \ud6c4\uc5d0\ub9cc \ud22c\uc5ec\ud55c\ub2e4. 2) \uc774 \uc57d\uc758 \uad6c\uc131\uc131\ubd84\uc774 \ubaa8\uc720\ub85c \ubd84\ube44\ub418\ub294\uc9c0 \uc5ec\ubd80\ub294 \ud655\uc778\ub418\uc9c0 \uc54a\uc558\uc73c\ubbc0\ub85c, \uc774 \uc57d\uc73c\ub85c \uc778\ud55c \uc7a0\uc7ac\uc801 \uc720\uc775\uc131\uc774 \uc720\uc544\uc5d0 \ub300\ud55c \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc131\uc744 \uc0c1\ud68c\ud558\uc9c0 \uc54a\ub294 \ud55c \uc774 \uc57d\uc744 \uc218\uc720\ubd80\uc5d0\uac8c \ud22c\uc5ec\ud574\uc11c\ub294 \uc548\ub41c\ub2e4.<\/p>\n\n\n\n

[\uc18c\uc544\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uc774 \uc57d\uc740 \uc18c\uc544\uc5d0 \ub300\ud55c \uc548\uc804\uc131 \ubc0f \uc720\ud6a8\uc131\uc774 \ud655\ub9bd\ub418\uc5b4 \uc788\uc9c0 \uc54a\uc73c\ubbc0\ub85c \ud22c\uc5ec\uac00 \uad8c\uc7a5\ub418\uc9c0 \uc54a\ub294\ub2e4. <\/p>\n\n\n\n

[\uace0\ub839\uc790\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uace0\ub839(\ub9cc 65\uc138 \uc774\uc0c1)\uc740 \uadfc\uc721\ubcd1\uc99d\uc5d0 \uac78\ub9ac\uae30 \uc26c\uc6b4 \uc694\uc778 \uc911 \ud558\ub098\uc774\ubbc0\ub85c \uc774 \uc57d\uc744 \uace0\ub839\uc790\uc5d0\uac8c \ud22c\uc5ec \uc2dc \uc8fc\uc758\ub97c \uae30\uc6b8\uc5ec\uc57c \ud55c\ub2e4. \uace0\ub839\uc790\uc5d0\uc11c \uc774 \uc57d\uc758 \uc6a9\ub7c9 \uc870\uc808\uc740 \ud544\uc694\ud558\uc9c0 \uc54a\ub2e4.<\/strong><\/p>\n\n\n\n

[\uac04\uc7a5\uc560 \ud658\uc790\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\ud65c\ub3d9\uc131 \uac04\uc9c8\ud658 \ub610\ub294 \uac04 \uc544\ubbf8\ub178\uc804\ub2ec\ud6a8\uc18c \uc218\uce58\uac00 \uc6d0\uc778\ubd88\uba85\uc73c\ub85c \uc9c0\uc18d\uc801\uc73c\ub85c \ub192\uc740 \ud658\uc790\uc5d0\ub294 \uc774 \uc57d\uc744 \ud22c\uc5ec\ud558\uc9c0 \uc54a\ub294\ub2e4(\u20182, \ub2e4\uc74c \ud658\uc790\uc5d0\ub294 \ud22c\uc5ec\ud558\uc9c0 \ub9d0 \uac83\u2019, \u20185. \uc77c\ubc18\uc801 \uc8fc\uc758\u2019 \ucc38\uc870)<\/p>\n\n\n\n

[\uc2e0\uc7a5\uc560 \ud658\uc790\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uc2e0\uc7a5\uc560\uc5d0 \ub300\ud55c \ubcd1\ub825\uc740 \ud6a1\ubb38\uadfc\uc735\ud574 \ubc1c\uc0dd\uc758 \uc704\ud5d8\uc778\uc790\uac00 \ub420 \uc218 \uc788\ub2e4. \uc774\ub7f0 \ud658\uc790\ub4e4\uc740 \uace8\uaca9\uadfc \ud6a8\uacfc\uc5d0 \ub300\ud55c \uba74\ubc00\ud55c \ubaa8\ub2c8\ud130\ub9c1\uc774 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\ub2e4(\u20185. \uc77c\ubc18\uc801 \uc8fc\uc758\u2019 \ucc38\uc870).<\/p>\n\n\n\n

\uac1c\uc815\uc77c 2026\ub144 03\uc6d4 03\uc77c<\/strong><\/strong><\/p>\n\n\n\n

<\/p>\n\n\n\n

\n
<\/div>\n\n\n\n
\n
\"\"<\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n

KR-ATO-116083 03\/2028<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

\uc544\ud1a0\uc82f \uc815 (\uc5d0\uc81c\ud2f0\ubbf8\ube0c\/\uc544\ud1a0\ub974\ubc14\uc2a4\ud0c0\ud2f4) 10\/10, 10\/20, 10\/40, 10\/80 mg [\ud6a8\ub2a5\u00b7\ud6a8\uacfc] \uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(\uc774\ud615\uc811\ud569 \uac00\uc871\ud615 \ubc0f \ube44\uac00\uc871\ud615) \ub610\ub294 \ud63c\ud569\ud615 \uc774\uc0c1\uc9c0\uc9c8\ud608\uc99d \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d \ucf5c\ub808\uc2a4\ud14c\ub864(total-C), LDL-\ucf5c\ub808\uc2a4\ud14c\ub864(LDL-C), \uc544\ud3ec B \ub2e8\ubc31(Apo B) \ubc0f \ud2b8\ub9ac\uae00\ub9ac\uc138\ub77c\uc774\ub4dc(TG) \ubc0f non-HDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0, HDL-\ucf5c\ub808\uc2a4\ud14c\ub864(HDL-C)\uc744 \uc99d\uac00\uc2dc\ud0a4\uae30 \uc704\ud55c \uc2dd\uc774\uc694\ubc95\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c \ud22c\uc5ec\ud55c\ub2e4. \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(HoFH) \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d\ucf5c\ub808\uc2a4\ud14c\ub864 \ubc0f LDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc744 \uac10\uc18c\uc2dc\ud0a4\uae30 \uc704\ud55c \ub2e4\ub978 \uc9c0\uc9c8\uc800\ud558 \uce58\ub8cc(\uc608, LDL-Apheresis)\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c, \ub610\ub294 \ub2e4\ub978 \uc9c0\uc9c8 […]<\/p>\n","protected":false},"author":36,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"personalization_user_type":[],"personalization_speciality_type":[],"footnotes":""},"class_list":["post-8733","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nAtozet Selected Safety Information - 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