{"id":8724,"date":"2023-04-05T09:19:05","date_gmt":"2023-04-05T09:19:05","guid":{"rendered":"https:\/\/organonpro.com\/kr-kr\/?page_id=8724"},"modified":"2026-03-23T06:21:40","modified_gmt":"2026-03-23T06:21:40","slug":"vytorin_ssi","status":"publish","type":"page","link":"https:\/\/organonpro.com\/ko-kr\/vytorin_ssi\/","title":{"rendered":"Vytorin Selected Safety Information"},"content":{"rendered":"\n

\ubc14\uc774\ud1a0\ub9b0\u2122 <\/sup>\uc815 <\/strong>(\uc5d0\uc81c\ud2f0\ubbf8\ube0c\/\uc2ec\ubc14\uc2a4\ud0c0\ud2f4) 10\/10, 10\/20, 10\/40 mg<\/strong><\/h2>\n\n\n\n

[\ud6a8\ub2a5\u00b7\ud6a8\uacfc]<\/strong><\/p>\n\n\n\n

\uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(\uc774\ud615\uc811\ud569 \uac00\uc871\ud615 \ubc0f \ube44\uac00\uc871\ud615) \ubc0f \ud63c\ud569\ud615 \uace0\uc9c0\ud608\uc99d \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d \ucf5c\ub808\uc2a4\ud14c\ub864(total-C), LDL-\ucf5c\ub808\uc2a4\ud14c\ub864(LDL-C), \uc544\ud3ec B \ub2e8\ubc31(Apo B) \ubc0f \ud2b8\ub9ac\uae00\ub9ac\uc138\ub77c\uc774\ub4dc(TG)\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0, HDL-\ucf5c\ub808\uc2a4\ud14c\ub864(HDL-C)\uc744 \uc99d\uac00\uc2dc\ud0a4\uae30 \uc704\ud55c \uc2dd\uc774\uc694\ubc95\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c \uc774 \uc57d\uc744 \ud22c\uc5ec\ud55c\ub2e4. \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(HoFH) \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(HoFH) \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d\ucf5c\ub808\uc2a4\ud14c\ub864 \ubc0f LDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc744 \uac10\uc18c\uc2dc\ud0a4\uae30 \uc704\ud55c \ub2e4\ub978 \uc9c0\uc9c8 \uc800\ud558 \uce58\ub8cc(\uc608, LDL Apheresis)\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c, \ub610\ub294 \ub2e4\ub978 \uc9c0\uc9c8 \uc800\ud558 \uce58\ub8cc\uac00 \uc720\uc6a9\ud558\uc9c0 \uc54a\uc740 \uacbd\uc6b0 \uc774 \uc57d\uc744 \ud22c\uc5ec\ud55c\ub2e4.<\/strong><\/p>\n\n\n\n

[\uc6a9\ubc95 \u00b7\uc6a9\ub7c9]<\/strong><\/p>\n\n\n\n

\uc774 \uc57d\uc744 \ud22c\uc5ec \uc804 \ubc0f \ud22c\uc5ec \uc911\uc778 \ud658\uc790\ub294 \ubc18\ub4dc\uc2dc \ud45c\uc900 \ucf5c\ub808\uc2a4\ud14c\ub864 \uc800\ud558\uc2dd\uc744 \ud574\uc57c \ud55c\ub2e4. \uc774 \uc57d\uc758 \ud22c\uc5ec\ub7c9\uc740 \ud658\uc790\uc758 LDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc758 \uae30\uc800\uce58, \uad8c\uc7a5\ub418\ub294 \uce58\ub8cc \ubaa9\ud45c\uce58 \ubc0f \ud658\uc790\uc758 \ubc18\uc751\uc5d0 \ub530\ub77c \uc870\uc808\ub418\uc5b4\uc57c \ud55c\ub2e4. \uc774 \uc57d\uc740 \uc2dd\uc0ac\uc640 \uad00\uacc4\uc5c6\uc774 1\uc77c 1\ud68c \uc800\ub141\uc5d0 \ud22c\uc5ec\ud55c\ub2e4. \uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d \ud658\uc790 \uc774 \uc57d\uc758 \uc6a9\ub7c9 \ubc94\uc704\ub294 1\uc77c 10\/10 mg ~ 10\/40 mg\uc774\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c \uad8c\uc7a5\ub418\ub294 \ucd08\ud68c \uc6a9\ub7c9\uc740 1\uc77c 10\/20 mg\uc774\ub2e4. LDL-\ucf5c\ub808\uc2a4\ud14c\ub864 \uac10\uc18c\uc758 \ud544\uc694\uc131\uc774 \uc801\uc740 \ud658\uc790\uc778 \uacbd\uc6b0 1\uc77c 10\/10 mg\uc73c\ub85c \uc2dc\uc791\ud560 \uc218 \uc788\ub2e4. \uc774 \uc57d\uc758 \ud22c\uc5ec\ub97c \uc2dc\uc791 \ud6c4 \ub610\ub294 \uc6a9\ub7c9 \uc801\uc815 \ud6c4, 4\uc8fc \uc774\uc0c1\uc758 \uac04\uaca9\uc744 \ub450\uace0 \ud608\uc911 \uc9c0\uc9c8\uce58\ub97c \ud655\uc778 \ud55c \ud6c4 \uc6a9\ub7c9\uc744 \uc870\uc808\ud55c\ub2e4. \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d \ud658\uc790 \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d \ud658\uc790\uc758 \uad8c\uc7a5 \uc6a9\ub7c9\uc740 1\uc77c 10\/40 mg\uc73c\ub85c, 1\uc77c 1\ud68c \uc800\ub141\uc5d0 \ud22c\uc5ec\ud55c\ub2e4. \uc774 \uc57d\uc740 \ub2e4\ub978 \uc9c0\uc9c8\uc800\ud558\uce58\ub8cc(\uc608, LDL Apheresis)\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c \ub610\ub294 \ub2e4\ub978 \uc9c0\uc9c8\uc800\ud558\uce58\ub8cc\uac00 \uc720\uc6a9\ud558\uc9c0 \uc54a\uc740 \uacbd\uc6b0 \ud22c\uc5ec\ud55c\ub2e4.<\/p>\n\n\n\n

[\uc0ac\uc6a9\uc0c1\uc758 \uc8fc\uc758\uc0ac\ud56d]<\/strong><\/p>\n\n\n\n

[\uae08\uae30]<\/strong><\/p>\n\n\n\n

1) \uc774 \uc57d\uc758 \uc131\ubd84\uc5d0 \uacfc\ubbfc\uc99d\uc778 \ud658\uc790. 2) \ud65c\ub3d9\uc131 \uac04\uc9c8\ud658 \ud658\uc790 \ud639\uc740 \ud608\uccad \uc544\ubbf8\ub178\uc804\ub2ec\ud6a8\uc18c \uc218\uce58\uac00 \uc6d0\uc778\ubd88\uba85\uc73c\ub85c \uc9c0\uc18d\uc801\uc73c\ub85c \ub192\uc740 \ud658\uc790(5. \uc77c\ubc18\uc801 \uc8fc\uc758 \ucc38\uc870). 3) \uc784\ubd80 \ubc0f \uc218\uc720\ubd80 \ub3d9\ub9e5\uacbd\ud654\uc99d\uc740 \ub9cc\uc131\uc9c8\ud658\uc774\uba70, \uc784\uc2e0 \uc911 \uc9c0\uc9c8\uc800\ud558\uc81c \ud22c\uc5ec\ub97c \uc911\uc9c0\ud574\ub3c4 \uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d\uc758 \uc7a5\uae30\uce58\ub8cc \uacb0\uacfc\uc5d0 \uc601\ud5a5\uc744 \uc8fc\uc9c0 \uc54a\ub294\ub2e4. \ub610\ud55c, \ucf5c\ub808\uc2a4\ud14c\ub864\uacfc \ucf5c\ub808\uc2a4\ud14c\ub864 \uc0dd\ud569\uc131 \uacbd\ub85c\uc758 \ub2e4\ub978 \uc0dd\uc131\ubb3c\uc740 \uc2a4\ud14c\ub85c\uc774\ub4dc, \uc138\ud3ec\ub9c9 \ud569\uc131 \ub4f1\uc758 \ud0dc\uc544 \ubc1c\ub2ec\uc5d0 \ud544\uc218\uc801\uc778 \uc131\ubd84\uc774\ub2e4. \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc744 \ud3ec\ud568\ud55c HMG-CoA \ud658\uc6d0\ud6a8\uc18c\uc800\ud574\uc81c\uac00 \ucf5c\ub808\uc2a4\ud14c\ub864 \ud569\uc131 \ubc0f \ucf5c\ub808\uc2a4\ud14c\ub864 \uc0dd\ud569\uc131\uacbd\ub85c\uc758 \ub2e4\ub978 \uc0dd\uc131\ubb3c\uc744 \uac10\uc18c\uc2dc\ud0ac \uc6b0\ub824\uac00 \uc788\uc73c\ubbc0\ub85c \uc784\ubd80 \ub610\ub294 \uc218\uc720\ubd80\uc5d0\uac8c \uc774 \uc57d\uc744 \ud22c\uc5ec\ud574\uc11c\ub294 \uc548 \ub41c\ub2e4. \uc774 \uc57d\uc744 \uac00\uc784 \uc5ec\uc131\uc5d0\uac8c \ud22c\uc5ec\ud560 \ub54c\uc5d0\ub294, \uc784\uc2e0\ud558\uc9c0 \uc54a\uc558\uc744 \uac00\ub2a5\uc131\uc774 \ub9e4\uc6b0 \ub192\uc744 \uacbd\uc6b0\uc5d0\ub9cc \ud22c\uc5ec\ud574\uc57c \ud55c\ub2e4. \uc774 \uc57d \ud22c\uc5ec \uc911 \uc784\uc2e0\uc774 \ud655\uc778\ub418\uba74 \uc989\uc2dc \ud22c\uc5ec\ub97c \uc911\uc9c0\ud558\uace0 \ud658\uc790\uc5d0\uac8c \ud0dc\uc544\uc5d0 \ub300\ud55c \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc131\uc744 \uc54c\ub824\uc57c \ud55c\ub2e4(7. \uc784\ubd80\uc5d0 \ub300\ud55c \ud22c\uc5ec \ubc0f 8. \uc218\uc720\ubd80\uc5d0 \ub300\ud55c \ud22c\uc5ec \ucc38\uc870). 4) \uac15\ub825\ud55c CYP3A4 \uc5b5\uc81c\uc81c(\uc608, \uc774\ud2b8\ub77c\ucf54\ub098\uc878, \ucf00\ud1a0\ucf54\ub098\uc878, \ud3ec\uc0ac\ucf54\ub098\uc878, \ubcf4\ub9ac\ucf54\ub098\uc878, HIV \ud504\ub85c\ud14c\uc544\uc81c \uc800\ud574\uc81c, \ubcf4\uc138\ud504\ub808\ube44\ub974, \ud154\ub77c\ud504\ub808\ube44\ub974, \uc5d0\ub9ac\ud2b8\ub85c\ub9c8\uc774\uc2e0, \ud074\ub77c\ub9ac\ud2b8\ub85c\ub9c8\uc774\uc2e0, \ud154\ub9ac\ud2b8\ub85c\ub9c8\uc774\uc2e0, \ub124\ud30c\uc870\ub3c8 \ubc0f \ucf54\ube44\uc2dc\uc2a4\ud0c0\ud2b8\ub97c \ud568\uc720\ud55c \uc758\uc57d\ud488)\ub97c \ud22c\uc5ec \uc911\uc778 \ud658\uc790(6. \uc0c1\ud638\uc791\uc6a9 \ucc38\uc870). 5) \uac9c\ud53c\ube0c\ub85c\uc9c8, \uc2dc\ud074\ub85c\uc2a4\ud3ec\ub9b0 \ub610\ub294 \ub2e4\ub098\uc878\uc744 \ud22c\uc5ec \uc911\uc778 \ud658\uc790(6. \uc0c1\ud638\uc791\uc6a9 \ucc38\uc870). 6) \uc774 \uc57d\uc740 \uc720\ub2f9\uc744 \ud568\uc720\ud558\uace0 \uc788\uc73c\ubbc0\ub85c, \uac08\ub77d\ud1a0\uc624\uc2a4 \ubd88\ub0b4\uc131(galactose intolerance), Lapp \uc720\ub2f9\ubd84\ud574\ud6a8\uc18c \uacb0\ud54d\uc99d(Lapp lactase deficiency) \ub610\ub294 \ud3ec\ub3c4\ub2f9-\uac08\ub77d\ud1a0\uc624\uc2a4 \ud761\uc218 \uc7a5\uc560(glucose-galactose malabsorption) \ub4f1\uc758 \uc720\uc804\uc801\uc778 \ubb38\uc81c\uac00 \uc788\ub294 \ud658\uc790\uc5d0\uac8c\ub294 \ud22c\uc5ec\ud558\uba74 \uc548 \ub41c\ub2e4.<\/p>\n\n\n\n

[\uc2e0\uc911\ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d \ub610\ub294 \uc548\uadfc \ubb34\ub825\uc99d \ud658\uc790 (\uac19\uc740 \uc885\ub958 \ub610\ub294 \ub2e4\ub978 \uc885\ub958\uc758 \uc2a4\ud0c0\ud2f4\uacc4 \uc57d\ubb3c\uc744 \ud22c\uc5ec\ud588\uc744 \ub54c \uc7ac\ubc1c\ud55c \uc0ac\ub840\uac00 \ubcf4\uace0\ub418\uc5c8\ub2e4. \u00a0<\/p>\n\n\n\n

[\uacbd\uace0]<\/strong><\/p>\n\n\n\n

1) \uadfc\uc721 \ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574 \uc774 \uc57d 10\/80 mg\/\uc77c\uae4c\uc9c0 \ud22c\uc5ec\ud55c \uc784\uc0c1\uc2dc\ud5d8 \uacb0\uacfc, \uc704\uc57d \ub300\uc870\uad70 \ub610\ub294 \ub2e8\ub3c5 \ud22c\uc5ec\ud55c HMG-CoA \ud658\uc6d0\ud6a8\uc18c\uc800\ud574\uc81c \ub300\uc870\uad70\uacfc \ube44\uad50\ud558\uc600\uc744 \ub54c, \uc5d0\uc81c\ud2f0\ubbf8\ube0c\uc5d0 \uc758\ud55c \uadfc\uc721 \ubcd1\uc99d \ub610\ub294 \ud6a1\ubb38\uadfc\uc735\ud574\ub294 \uc704\uc57d \ub300\uc870\uad70 \ub610\ub294 HMG-CoA \ud658\uc6d0\ud6a8\uc18c\uc800\ud574\uc81c \ub300\uc870\uad70\ubcf4\ub2e4 \ub192\uc9c0 \uc54a\uc558\ub2e4. \uadf8\ub7ec\ub098, \uadfc\uc721 \ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574\ub294 HMG-CoA \ud658\uc6d0\ud6a8\uc18c\uc800\ud574\uc81c \ubc0f \ub2e4\ub978 \uc9c0\uc9c8\uc800\ud558\uc81c\uc758 \uc798 \uc54c\ub824\uc9c4 \uc774\uc0c1\ubc18\uc751\uc774\ub2e4. \uc784\uc0c1\uc2dc\ud5d8 \uacb0\uacfc, \uc774 \uc57d\uc5d0\uc11c \ud06c\ub808\uc544\ud2f4\ud0a4\ub098\uc544\uc81c(CK) \uc0c1\uc2b9(\uc815\uc0c1\uc0c1\ud55c\uce58\uc758 10\ubc30 \uc774\uc0c1)\uc758 \ubc1c\ud604\uc728\uc740 0.2%\uc600\ub2e4. \ud6a1\ubb38\uadfc\uc735\ud574\ub97c \ud3ec\ud568\ud55c \uadfc\uc721 \ubcd1\uc99d\uc740 \uc6a9\ub7c9\uacfc \uc5f0\uad00\uc774 \uc788\ub2e4. \ud6a1\ubb38\uadfc\uc735\ud574\ub97c \ud3ec\ud568\ud55c \uadfc\uc721 \ubcd1\uc99d\uc758 \uc704\ud5d8\uc131\uc740 \uc720\uc0ac\ud55c LDL-\ucf5c\ub808\uc2a4\ud14c\ub864 \uac10\uc18c \ud6a8\ub2a5\uc744 \uac00\uc9c4 \ub2e4\ub978 \uc2a4\ud0c0\ud2f4\uacc4 \uc57d\ubb3c \uce58\ub8cc \ub610\ub294 \uc800\uc6a9\ub7c9\uc758 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc5d0 \ube44\ud574 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4 80 mg\uc744 \ubcf5\uc6a9\ud558\ub294 \ud658\uc790\uad70\uc5d0\uc11c \ub354 \ub192\ub2e4. \uadf8\ub7ec\ubbc0\ub85c \uc774 \uc57d 10\/80 mg\uc744 \ubcf5\uc6a9\ud558\ub294 \ud658\uc790\uac00 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uacfc \uc0c1\ud638\uc791\uc6a9\ud558\ub294 \uc57d\ubb3c\uc744 \ubcf5\uc6a9\ud574\uc57c \ud558\ub294 \uacbd\uc6b0, \uc800\uc6a9\ub7c9\uc758 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4 \ub610\ub294 \uc57d\ubb3c \uc0c1\ud638\uc791\uc6a9 \uac00\ub2a5\uc131\uc774 \ub0ae\uc740 \ub2e4\ub978 \uc2a4\ud0c0\ud2f4\uacc4 \uc57d\ubb3c\uc744 \ud22c\uc5ec\ud574\uc57c \ud55c\ub2e4(5. \uc77c\ubc18\uc801 \uc8fc\uc758, \uadfc\uc721 \ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574 \ud56d \ucc38\uc870).<\/p>\n\n\n\n

[\uc774\uc0c1\ubc18\uc751]<\/strong><\/p>\n\n\n\n

\uc774 \uc57d(\ub610\ub294 \uc774 \uc57d\uacfc \ub3d9\ub4f1\ud55c \uc5d0\uc81c\ud2f0\ubbf8\ube0c\uc640 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc758 \ubcd1\uc6a9\ud22c\uc5ec)\uc5d0 \ub300\ud55c \uc548\uc804\uc131\uc740 \uc784\uc0c1\uc2dc\ud5d8\uc5d0 \ucc38\uc5ec\ud55c 10,189\uba85 \uc774\uc0c1\uc758 \ud658\uc790\uc5d0\uc11c \ud3c9\uac00\ub418\uc5c8\ub2e4. \uc774 \uc57d\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \ub0b4\uc57d\uc131\uc774 \uc6b0\uc218\ud558\uc600\ub2e4. \uc5d0\uc81c\ud2f0\ubbf8\ube0c (\ub2e8\uc77c\uc81c \ud5c8\uac00\uc0ac\ud56d \ucc38\uc870) \uc704\uc57d\ub300\uc870 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c, \uc778\uacfc\uad00\uacc4\uc758 \ud3c9\uac00\uc640 \uad00\uacc4\uc5c6\uc774 \ubcf4\uace0\ub41c \uc5d0\uc81c\ud2f0\ubbf8\ube0c\uc758 \uc8fc\uc694 \uc774\uc0c1\ubc18\uc751\uc740 \ub2e4\uc74c\uacfc \uac19\ub2e4. \uc804\uc2e0: \ud53c\ub85c, \uc18c\ud654\uae30\uacc4: \ubcf5\ud1b5, \uc124\uc0ac, \uac10\uc5fc: \ubc14\uc774\ub7ec\uc2a4 \uac10\uc5fc, \uc778\ub450\uc5fc, \ubd80\ube44\ub3d9\uc5fc, \uadfc-\uace8\uaca9\uacc4: \uad00\uc808\ud1b5, \uc694\ud1b5, \ud638\ud761\uae30\uacc4 \uc774\uc0c1: \uae30\uce68. \uc2dc\ud310 \ud6c4 \uc774\uc0c1\ubc18\uc751. \ub2e4\uc74c\uc758 \uc774\uc0c1\ubc18\uc751\uc774 \uc778\uacfc\uad00\uacc4 \ud3c9\uac00\uc640 \uad00\uacc4\uc5c6\uc774 \uc2dc\ud310 \ud6c4 \ubcf4\uace0\ub418\uc5c8\ub2e4. \uc544\ub098\ud544\ub77d\uc2dc\uc2a4, \ub450\ub4dc\ub7ec\uae30, \ubc1c\uc9c4 \ubc0f \ud608\uad00 \ubd80\uc885\uc744 \ud3ec\ud568\ud55c \uacfc\ubbfc\ubc18\uc751, \uad00\uc808\ud1b5, \uadfc\uc721\ud1b5, \ud06c\ub808\uc544\ud2f4\ud3ec\uc2a4\ud3ec\ud0a4\ub098\uc81c\uce58\uc758 \uc0c1\uc2b9, \uadfc\uc721\ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574(\u20185. \uc77c\ubc18\uc801 \uc8fc\uc758\u2019 \ud56d \ucc38\uc870), \uac04 \uc544\ubbf8\ub178\uc804\uc774\ud6a8\uc18c \uc218\uce58\uc758 \uc0c1\uc2b9, \uac04\uc5fc, \ubcf5\ud1b5, \ud608\uc18c\ud310 \uac10\uc18c\uc99d, \uc624\uc2ec, \ucdcc\uc7a5\uc5fc, \uc5b4\uc9c0\ub7ec\uc6c0, \uac10\uac01\uc774\uc0c1, \uc6b0\uc6b8\uc99d, \ub450\ud1b5, \ub2f4\uc11d\uc99d, \ub2f4\ub0ad\uc5fc, \ud53c\ubd80\uc810\ub9c9\uc548\uc99d\ud6c4\uad70(\uc2a4\ud2f0\ube10\uc2a4-\uc874\uc2a8 \uc99d\ud6c4\uad70) \ubc0f \ub3c5\uc131\ud45c\ud53c\uad34\uc0ac\uc6a9\ud574(\ub77c\uc774\uc5d8 \uc99d\ud6c4\uad70), \ud638\uc0b0\uad6c \uc99d\uac00 \ubc0f \uc804\uc2e0 \ubc18\uc751 \ub3d9\ubc18 \uc57d\ubb3c \ubc18\uc751(DRESS), \ub2e4\ud615\uc131 \ud64d\ubc18\uc744 \ud3ec\ud568\ud55c \uc911\uc99d \ud53c\ubd80 \uc774\uc0c1 \ubc18\uc751(SCARs)\uc2ec\ubc14\uc2a4\ud0c0\ud2f4 (\ub2e8\uc77c\uc81c \ud5c8\uac00\uc0ac\ud56d \ucc38\uc870), \uc57d\ubb3c-\uc720\ubc1c \uac04 \uc190\uc0c1. \uc2ec\ubc14\uc2a4\ud0c0\ud2f4 (\ub2e8\uc77c\uc81c \ud5c8\uac00\uc0ac\ud56d \ucc38\uc870) \uc704\uc57d\ub300\uc870 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c, \uc778\uacfc\uad00\uacc4\uc758 \ud3c9\uac00\uc640 \uad00\uacc4\uc5c6\uc774 \ubcf4\uace0\ub41c \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc758 \uc8fc\uc694 \uc774\uc0c1\ubc18\uc751\uc740 \ub2e4\uc74c\uacfc \uac19\ub2e4. \uc804\uc2e0: \ubb34\ub825\uc99d, \ub208: \ubc31\ub0b4\uc7a5, \uc18c\ud654\uae30\uacc4: \ubcf5\ud1b5, \ubcc0\ube44, \uc124\uc0ac, \uc18c\ud654\ubd88\ub7c9, \ubc29\uadc0, \uad6c\uc5ed, \ud53c\ubd80 \ubc0f \ud53c\ud558\uc870\uc9c1: \uc2b5\uc9c4, \uac00\ub824\uc6c0\uc99d, \ubc1c\uc9c4. \uc2a4\ud0c0\ud2f4\uacc4 \uc57d\ubb3c \ud22c\uc5ec\uc640 \uad00\ub828\ud558\uc5ec \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d \ub610\ub294 \uc548\uadfc \ubb34\ub825\uc99d\uc758 \uc720\ubc1c \ub610\ub294 \uc545\ud654\uac00 \ubcf4\uace0\ub418\uc5c8\ub2e4 (\u20183. \ub2e4\uc74c \ud658\uc790\uc5d0\ub294 \uc2e0\uc911\ud788 \ud22c\uc5ec\ud560 \uac83\u2019\ud56d \ubc0f \u20185. \uc77c\ubc18\uc801 \uc8fc\uc758 2) \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d\/\uc548\uadfc \ubb34\ub825\uc99d\u2019\ud56d \ucc38\uc870).\u00a0<\/p>\n\n\n\n

[\uc77c\ubc18\uc801 \uc8fc\uc758]<\/strong><\/p>\n\n\n\n

1) \uadfc\uc721\ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc740 \ub2e4\ub978 HMG-CoA \ud658\uc6d0\ud6a8\uc18c\uc800\ud574\uc81c\uc640 \ub9c8\ucc2c\uac00\uc9c0\ub85c \uadfc\uc721 \ubcd1\uc99d\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\ub2e4. \ub2e4\ub978 HMG-CoA \ud658\uc6d0 \ud6a8\uc18c \uc800\ud574\uc81c\uc640 \uac19\uc774 \uadfc\uc721 \ubcd1\uc99d\/\ud6a1\ubb38\uadfc\uc735\ud574\uc758 \uc704\ud5d8\uc131\uc740 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4 \uc6a9\ub7c9\uacfc \uad00\ub828\uc774 \uc788\ub2e4. \ub2f5\ud1a0\ub9c8\uc774\uc2e0\uacfc HMG-CoA \ud658\uc6d0 \ud6a8\uc18c \uc5b5\uc81c\uc81c\ub97c \ubcd1\uc6a9 \ud22c\uc5ec\ud558\uc600\uc744 \ub54c \uadfc\uc721 \ubcd1\uc99d \ubc0f\/\ub610\ub294 \ud6a1\ubb38\uadfc\uc735\ud574\uac00 \ubcf4\uace0\ub418\uc5c8\ub2e4. \ub2f5\ud1a0\ub9c8\uc774\uc2e0 \ubc0f HMG-CoA \ud658\uc6d0 \ud6a8\uc18c \uc5b5\uc81c\uc81c \uac01\uac01 \ub2e8\ub3c5 \ud22c\uc5ec \uc2dc \uadfc\uc721 \ubcd1\uc99d \ubc0f\/\ub610\ub294 \ud6a1\ubb38\uadfc\uc735\ud574\uac00 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc73c\ubbc0\ub85c \ubcd1\uc6a9 \ud22c\uc5ec \uc2dc \uc8fc\uc758\ub97c \uae30\uc6b8\uc5ec\uc57c \ud55c\ub2e4. \ub2f5\ud1a0\ub9c8\uc774\uc2e0\uc744 \ud22c\uc5ec \uc911\uc778 \ud658\uc790\uc5d0\uc11c \uc77c\uc2dc\uc801\uc73c\ub85c \uc774 \uc57d\uc758 \ud22c\uc5ec\ub97c \uc911\ub2e8\ud558\ub294 \uac83\uc744 \uace0\ub824\ud574\uc57c \ud55c\ub2e4(6. \uc0c1\ud638\uc791\uc6a9 \ucc38\uc870). 2) \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d\/\uc548\uadfc \ubb34\ub825\uc99d: \ub4dc\ubb3c\uac8c \uc2a4\ud0c0\ud2f4\uacc4 \uc57d\ubb3c\uc774 \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d \ub610\ub294 \uc548\uadfc \ubb34\ub825\uc99d\uc744 \uc720\ubc1c\ud558\uac70\ub098 \uc545\ud654\uc2dc\ud0ac \uc218 \uc788\ub2e4(\u20184. \uc774\uc0c1\ubc18\uc751\u2019\ud56d \ucc38\uc870). \uc774 \uc57d\uc740 \uc774\ub7ec\ud55c \uc0c1\ud0dc\uc758 \ud658\uc790\uc5d0\uac8c \uc8fc\uc758\ud574\uc11c \uc0ac\uc6a9\ud574\uc57c \ud55c\ub2e4. (\u20183. \ub2e4\uc74c \ud658\uc790\uc5d0\ub294 \uc2e0\uc911\ud788 \ud22c\uc5ec\ud560 \uac83\u2019\ud56d \ucc38\uc870). \uc911\uc99d \uadfc\uc721 \ubb34\ub825\uc99d \ub610\ub294 \uc548\uadfc \ubb34\ub825\uc99d\uc774 \uc720\ubc1c\ub418\uac70\ub098 \uc545\ud654\ub41c \uacbd\uc6b0 \ud22c\uc5ec\ub97c \uc911\ub2e8\ud574\uc57c\ud55c\ub2e4. 3) \uac04 \uae30\ub2a5 \uc774\uc0c1 \ud658\uc790 3\uac1c\uc758 \uc704\uc57d\ub300\uc870, 12\uc8fc \uc784\uc0c1\uc2dc\ud5d8\uacb0\uacfc, \ud608\uccad \uc544\ubbf8\ub178\uc804\ub2ec\ud6a8\uc18c \uc218\uce58\uc758 \uc9c0\uc18d\uc801 \uc0c1\uc2b9(\uc815\uc0c1\uc0c1\ud55c\uce58\uc758 3\ubc30 \uc774\uc0c1)\uc758 \ubc1c\ud604\uc728\uc740 \uc774 \uc57d\uc744 \ud22c\uc5ec\ud55c \uc804\uccb4 \ud658\uc790\uc5d0\uc11c 1.7%\uc600\uc73c\ub098, \uc774 \uc57d 10\/80 mg\uc744 \ud22c\uc5ec\ud55c \ud658\uc790\uc5d0\uc11c\ub294 2.6%\ub85c \uc6a9\ub7c9\uacfc \uad00\ub828 \uc788\uac8c \ub098\ud0c0\ub0ac\ub2e4. 4) \ud658\uc790\ub97c \uc704\ud55c \uc815\ubcf4 \ud658\uc790\uc5d0\uac8c \uc774 \uc57d\uacfc \ubcd1\uc6a9\ud22c\uc5ec\ud560 \uc218 \uc5c6\ub294 \uc57d\ubb3c\uc5d0 \ub300\ud574 \uc54c\ub9ac\uace0, \uc774 \uc57d \ud22c\uc5ec \uc911 \uc124\uba85\ub418\uc9c0 \uc54a\ub294 \uadfc\uc721\ud1b5, \uc555\ud1b5, \uadfc\uc721 \uc57d\ud654\uac00 \uc0dd\uae30\uac70\ub098 \uc774 \uc57d \ud22c\uc5ec \uc911\uc9c0 \ud6c4\uc5d0\ub3c4 \uadfc\uc721\uc758 \uc9d5\ud6c4\ub098 \uc99d\uc0c1\uc774 \uc9c0\uc18d\ub41c\ub2e4\uba74 \uc989\uc2dc \uc758\uc0ac\uc5d0\uac8c \uc54c\ub9ac\ub3c4\ub85d \ud574\uc57c \ud55c\ub2e4. 5) \uac04 \ubd80\uc804 \ud658\uc790 \uc911\ub4f1\ub3c4 \ub0b4\uc9c0 \uc911\uc99d\uc758 \uac04\ubd80\uc804 \ud658\uc790\uc5d0\ub294 \uc774 \uc57d\uc5d0 \ub300\ud55c \ub178\ucd9c\uc774 \uc99d\uac00\ud558\uc5ec \uc608\uc0c1\uce58 \ubabb\ud55c \ud6a8\uacfc\uac00 \ub098\ud0c0\ub0a0 \uc218 \uc788\uc73c\ubbc0\ub85c, \uc774 \uc57d\uc774 \uad8c\uc7a5\ub418\uc9c0 \uc54a\ub294\ub2e4. 6) \uac04\uc9c8\uc131 \ud3d0\uc9c8\ud658 \uc77c\ubd80 \uc2a4\ud0c0\ud2f4\uacc4\uc5f4 \uc57d\ubb3c\uacfc \uad00\ub828\ud558\uc5ec \ud2b9\ud788 \uc7a5\uae30 \ud22c\uc5ec \uc2dc \uac04\uc9c8\uc131 \ud3d0\uc9c8\ud658\uacfc \uac19\uc740 \uc774\ub840\uc801\uc778 \uc0ac\ub840\uac00 \ubcf4\uace0\ub41c \ubc14 \uc788\ub2e4. \ud658\uc790\uac00 \uac04\uc9c8\uc131 \ud3d0\uc9c8\ud658\uc73c\ub85c\uc758 \ubc1c\uc804\uc774 \uc758\uc2ec\ub420 \uacbd\uc6b0\uc5d0\ub294 \uc2a4\ud0c0\ud2f4 \uc57d\ubb3c \uce58\ub8cc\ub97c \uc911\ub2e8\ud558\uc5ec\uc57c \ud55c\ub2e4. 7) \ubc1c\uc554\uc131, \ubcc0\uc774\uc6d0\uc131, \uc0dd\uc2dd\ub3c5\uc131\uc774 \uc57d\uc758 \ubc1c\uc554\uc131 \ub610\ub294 \uc0dd\uc2dd\ub3c5\uc131\uc5d0 \ub300\ud55c \uc804\uc784\uc0c1 \uc2dc\ud5d8\uc740 \uc218\ud589\ub418\uc9c0 \uc54a\uc558\ub2e4. 8) \ub2f9\ub1e8\ubcd1 \ud5a5\ud6c4 \ub2f9\ub1e8\ubcd1\uc758 \uc704\ud5d8\uc131\uc774 \ub192\uc740 \uba87\uba87 \ud658\uc790\uc5d0\uac8c \ud608\ub2f9\uc744 \uc0c1\uc2b9\uc2dc\ud0a4\ub294 \uc57d\ubb3c\uad70\uc778 \uc2a4\ud0c0\ud2f4\uc744 \ud22c\uc5ec\ud588\uc744 \ub54c, \ub2f9\ub1e8\ubcd1\uc758 \uc815\uaddc \uce58\ub8cc\uac00 \ud544\uc694\ud55c \uc815\ub3c4\ub85c \uace0\ud608\ub2f9\uc99d\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\ub2e4\ub294 \uc810\uc774 \uba87\uba87 \uc99d\uac70\uc5d0\uc11c \uc81c\uc2dc\ub41c \ubc14 \uc788\ub2e4. \uadf8\ub7ec\ub098, \uc2a4\ud0c0\ud2f4\uc758 \ud22c\uc5ec\ub85c \uc778\ud55c \ud608\uad00 \uc704\ud5d8\uc131\uc758 \uac10\uc18c\uac00 \uc774\ub7ec\ud55c \uc704\ud5d8\uc131\uc744 \uc0c1\ud68c\ud558\ubbc0\ub85c, \uc774\ub294 \uc2a4\ud0c0\ud2f4\uc758 \ud22c\uc5ec\ub97c \uc911\ub2e8\ud558\ub294 \uc0ac\uc720\uac00 \ub420 \uc218 \uc5c6\ub2e4. \uac01 \uad6d\uac00\ubcc4 \uaddc\uc815\uc5d0 \uadfc\uac70\ud558\uc5ec \uc704\ud5d8\uc131\uc744 \ubcf4\uc720\ud55c \ud658\uc790(\uacf5\ubcf5\ud608\ub2f9 5.6~6.9 mmol\/L, BMI>30 kg\/\u33a1, \ud2b8\ub9ac\uae00\ub9ac\uc138\ub77c\uc774\ub4dc\uc758 \uc99d\uac00, \uace0\ud608\uc555)\ub97c \uc784\uc0c1\uc801 \ubc0f \uc0dd\ud654\ud559\uc801\uc73c\ub85c \ubaa8\ub2c8\ud130\ub9c1 \ud574\uc57c \ud55c\ub2e4.<\/p>\n\n\n\n

[\uc0c1\ud638 \uc791\uc6a9]<\/strong><\/p>\n\n\n\n

\uc774 \uc57d\uc758 \uc8fc\uc131\ubd84 \uc911 \ud558\ub098\uc778 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc740\u00a0CYP3A4\uc5d0 \uc758\ud574 \ub300\uc0ac \ub418\uba70 \uac04 \ud761\uc218 \uc57d\ubb3c\uc218\uc1a1\uccb4\uc778\u00a0OATP1B1\uacfc \uac19\uc740 \uc218\uc1a1\uccb4 \ub2e8\ubc31\uc9c8\uc758 \uae30\uc9c8\uc774\ub2e4. \uadf8\ub7ec\ubbc0\ub85c \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uacfc\u00a0CYP3A4 \uc800\ud574\uc81c \ub610\ub294 \uc218\uc1a1\uccb4 \ub2e8\ubc31\uc9c8 \uc5b5\uc81c\uc81c\uc640 \ubcd1\uc6a9\ud22c\uc5ec \uc2dc \uc2ec\ubc14\uc2a4\ud0c0\ud2f4 \ubc0f \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc0b0\uc758 \ud608\uc7a5 \ub18d\ub3c4\uac00 \uc99d\uac00\ud558\uc5ec \uadfc\uc721 \ubcd1\uc99d\uc758 \uc704\ud5d8\uc774 \uc99d\uac00\ud560 \uc218 \uc788\ub2e4.<\/p>\n\n\n\n

[\uc784\ubd80 \ubc0f \uc218\uc720\ubd80\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc758 \uc784\ubd80\uc5d0 \ub300\ud55c \uc548\uc804\uc131\uc740 \ud655\ub9bd\ub418\uc5b4 \uc788\uc9c0 \uc54a\ub2e4. \uc784\ubd80\ub97c \ub300\uc0c1\uc73c\ub85c \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc744 \ud22c\uc5ec\ud55c \ub300\uc870\uc784\uc0c1\uc2dc\ud5d8\uc740 \uc218\ud589\ub418\uc9c0 \uc54a\uc558\ub2e4. \uc774 \uc57d\uc740 \uc784\ubd80 \ub610\ub294 \uc784\uc2e0\uc744 \uc6d0\ud558\ub294 \uc5ec\uc131 \ubc0f \uc784\uc2e0 \ud560 \uac00\ub2a5\uc131\uc774 \uc788\ub294 \uc5ec\uc131\uc5d0\uac8c\ub294 \uc774 \uc57d\uc744 \uc0ac\uc6a9\ud574\uc11c\ub294 \uc548 \ub41c\ub2e4. \uc784\uc2e0 \uae30\uac04 \ub3d9\uc548 \uc774 \uc57d\uc758 \ud22c\uc5ec\ub97c \ubcf4\ub958\ud558\uac70\ub098, \uc784\uc2e0\uc744 \ud558\uc9c0 \uc54a\uc544\uc57c \ud55c\ub2e4. \ub7ab\ud2b8 \uc2e4\ud5d8\uc5d0\uc11c \uc218\uc720 \uc911\uc778 \uc0c8\ub07c\uc758 \ucd1d \uc5d0\uc81c\ud2f0\ubbf8\ube0c\uc5d0 \ub300\ud55c \ub178\ucd9c\uc774 \ubaa8\uccb4 \ud608\uc7a5\uc5d0\uc11c \uad00\ucc30\ub418\ub294 \uac12\uc758 \uc808\ubc18\uc5d0 \uc774\ub974\ub800\ub2e4. \uc5d0\uc81c\ud2f0\ubbf8\ube0c\uc640 \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc774 \uc0ac\ub78c\uc758 \ubaa8\uc720\ub85c \ubd84\ube44\ub418\ub294\uc9c0 \uc5ec\ubd80\ub294 \uc54c\ub824\uc9c0\uc9c0 \uc54a\uc558\ub2e4. \uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc758 \ubaa8\uc720\ub85c\uc758 \uc774\ud589\uc740 \uc54c\ub824\uc9c4 \ubc14 \uc5c6\uc73c\ub098 \uac19\uc740 \uc885\ub958\uc758 \ub2e4\ub978 \uc57d\uc5d0\uc11c \uc18c\ub7c9 \ubaa8\uc720 \uc911\uc73c\ub85c\uc758 \uc774\ud589\uc774 \ubcf4\uace0\ub418\uc5b4 \uc788\uace0 \ubaa8\uc720\ub85c \uc774\ud589\uc2dc \uc720\uc544\uc5d0\uac8c \uc2ec\uac01\ud55c \uc774\uc0c1\ubc18\uc751\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc73c\ubbc0\ub85c \uc774 \uc57d\uc744 \ud22c\uc5ec\ud558\ub294 \uacbd\uc6b0 \uc218\uc720\ub97c \uc911\uc9c0\ud55c\ub2e4(2. \ub2e4\uc74c \ud658\uc790\uc5d0\ub294 \ud22c\uc5ec\ud558\uc9c0 \ub9d0 \uac83 \ucc38\uc870).<\/p>\n\n\n\n

[\uc18c\uc544\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uc18c\uc544 \ud658\uc790\uc5d0 \ub300\ud55c \uc548\uc804\uc131 \ubc0f \uc720\ud6a8\uc131 \uc790\ub8cc\ub294 \ubd88\ucda9\ubd84\ud558\ub2e4<\/p>\n\n\n\n

[\uace0\ub839\uc790\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c, \uc774 \uc57d\uc744 \ud22c\uc5ec\ud55c \ud658\uc790 \uc911 792\uba85\uc774 65\uc138 \uc774\uc0c1\uc774\uc5c8\ub2e4(176\uba85\uc758 \ud658\uc790\ub294 75\uc138 \uc774\uc0c1\uc774\uc5c8\uc74c). \uc774 \uc57d\uc758 \uc548\uc804\uc131\uc740 \uace0\ub839\uc790 \ud658\uc790\uc640 \uc80a\uc740 \ud658\uc790 \uac04\uc5d0 \uc720\uc0ac\ud558\uc600\uc73c\ub098, \uc77c\ubd80 \uace0\ub839\uc790 \ud658\uc790\uc5d0\uc11c \ubcf4\ub2e4 \ubbfc\uac10\ud55c \ubc18\uc751\uc774 \ub098\ud0c0\ub0a0 \uc218 \uc788\uc74c\uc744 \ubc30\uc81c\ud560 \uc218 \uc5c6\ub2e4(4. \uc774\uc0c1\ubc18\uc751 \ucc38\uc870).<\/p>\n\n\n\n

[\uac04\uc7a5\uc560 \ud658\uc790\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uacbd\uc99d\uc758 \uac04\uc7a5\uc560 \ud658\uc790\uc758 \uacbd\uc6b0 \uc6a9\ub7c9 \uc870\uc808\uc774 \ud544\uc694\ud558\uc9c0 \uc54a\uc73c\ub098, \uc911\ub4f1\ub3c4 \ub610\ub294 \uc911\uc99d\uc758 \uac04\uc7a5\uc560 \ud658\uc790\uc758 \uacbd\uc6b0 \uc774 \uc57d\uc758 \ud22c\uc5ec\uac00 \uad8c\uc7a5\ub418\uc9c0 \uc54a\ub294\ub2e4(\uc0ac\uc6a9\uc0c1\uc758 \uc8fc\uc758\uc0ac\ud56d \uc911 5. \uc77c\ubc18\uc801 \uc8fc\uc758, \uac04\uae30\ub2a5 \uc774\uc0c1 \ud658\uc790 \ud56d \ucc38\uc870).<\/p>\n\n\n\n

[\uc2e0\uc7a5\uc560 \ubc0f \ub9cc\uc131 \uc2e0\uc7a5\uc9c8\ud658\uc744 \ub3d9\ubc18\ud55c \ud658\uc790\uc5d0 \ub300\ud55c \ud22c\uc5ec]<\/strong><\/p>\n\n\n\n

\uacbd\uc99d\uc758 <\/strong>\uc2e0\uc7a5\uc560(\ucd94\uc815 \uc0ac\uad6c\uccb4\uc5ec\uacfc\uc728(eGFR) \u226560 mL\/min\/1.73 \u33a1) \ud658\uc790\uc758 \uacbd\uc6b0 \uc6a9\ub7c9 \uc870\uc808\uc774 \ud544\uc694\ud558\uc9c0 \uc54a\ub2e4. \ub9cc\uc131 \uc2e0\uc7a5 \uc9c8\ud658\uc744 \ub3d9\ubc18\ud558\uace0 \ucd94\uc815 \uc0ac\uad6c\uccb4 \uc5ec\uacfc\uc728 <60 mL\/min\/1.73 \u33a1\uc778 \ud658\uc790\uc758 \uacbd\uc6b0, \uc774 \uc57d 10\/20 mg\uc744 1\uc77c 1\ud68c \uc800\ub141\uc5d0 \ud22c\uc5ec\ud55c\ub2e4. \uc774\ub7ec\ud55c \ud658\uc790\uc5d0\uac8c \uc774 \uc57d\uc744 \ub354 \ub192\uc740 \uc6a9\ub7c9\uc73c\ub85c \ud22c\uc5ec\ud560 \ub54c\uc5d0\ub294 \uc2e0\uc911\ud788 \ud22c\uc5ec\ud558\uc5ec\uc57c \ud558\uba70 \uc138\uc2ec\ud788 \ubaa8\ub2c8\ud130\ub9c1 \ud574\uc57c \ud55c\ub2e4(\uc0ac\uc6a9\uc0c1\uc758 \uc8fc\uc758\uc0ac\ud56d \uc911 5. \uc77c\ubc18\uc801 \uc8fc\uc758 \ucc38\uc870).<\/p>\n\n\n\n

<\/p>\n\n\n\n

\uac1c\uc815\uc77c 2025\ub144 08\uc6d4 29\uc77c<\/strong><\/strong><\/strong><\/p>\n\n\n\n

\u203b \ucc98\ubc29\ud558\uc2dc\uae30 \uc804\uc5d0 \uac01 \ud56d\ubaa9\uc5d0 \ub300\ud55c \uc790\uc138\ud55c \ub0b4\uc6a9\uc740 \uc81c\ud488\uc124\uba85\uc11c \uc804\ubb38\uc744 \ucc38\uc870\ud558\uc2dc\uae30 \ubc14\ub78d\ub2c8\ub2e4.<\/strong><\/p>\n\n\n\n

KR-EZS-110050 08\/2027<\/p>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div>\n\n\n\n
\n
\"\"<\/figure>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\ubc14\uc774\ud1a0\ub9b0\u2122 \uc815 (\uc5d0\uc81c\ud2f0\ubbf8\ube0c\/\uc2ec\ubc14\uc2a4\ud0c0\ud2f4) 10\/10, 10\/20, 10\/40 mg [\ud6a8\ub2a5\u00b7\ud6a8\uacfc] \uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(\uc774\ud615\uc811\ud569 \uac00\uc871\ud615 \ubc0f \ube44\uac00\uc871\ud615) \ubc0f \ud63c\ud569\ud615 \uace0\uc9c0\ud608\uc99d \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d \ucf5c\ub808\uc2a4\ud14c\ub864(total-C), LDL-\ucf5c\ub808\uc2a4\ud14c\ub864(LDL-C), \uc544\ud3ec B \ub2e8\ubc31(Apo B) \ubc0f \ud2b8\ub9ac\uae00\ub9ac\uc138\ub77c\uc774\ub4dc(TG)\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0, HDL-\ucf5c\ub808\uc2a4\ud14c\ub864(HDL-C)\uc744 \uc99d\uac00\uc2dc\ud0a4\uae30 \uc704\ud55c \uc2dd\uc774\uc694\ubc95\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c \uc774 \uc57d\uc744 \ud22c\uc5ec\ud55c\ub2e4. \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(HoFH) \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(HoFH) \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d\ucf5c\ub808\uc2a4\ud14c\ub864 \ubc0f LDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc744 \uac10\uc18c\uc2dc\ud0a4\uae30 \uc704\ud55c \ub2e4\ub978 \uc9c0\uc9c8 \uc800\ud558 \uce58\ub8cc(\uc608, LDL Apheresis)\uc758 […]<\/p>\n","protected":false},"author":36,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"personalization_user_type":[],"personalization_speciality_type":[],"footnotes":""},"class_list":["post-8724","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nVytorin Selected Safety Information - Organon Pro - Korea<\/title>\n<meta name=\"robots\" content=\"index, nofollow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/organonpro.com\/ko-kr\/vytorin_ssi\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vytorin Selected Safety Information\" \/>\n<meta property=\"og:description\" content=\"\ubc14\uc774\ud1a0\ub9b0\u2122 \uc815 (\uc5d0\uc81c\ud2f0\ubbf8\ube0c\/\uc2ec\ubc14\uc2a4\ud0c0\ud2f4) 10\/10, 10\/20, 10\/40 mg [\ud6a8\ub2a5\u00b7\ud6a8\uacfc] \uc6d0\ubc1c\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(\uc774\ud615\uc811\ud569 \uac00\uc871\ud615 \ubc0f \ube44\uac00\uc871\ud615) \ubc0f \ud63c\ud569\ud615 \uace0\uc9c0\ud608\uc99d \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d \ucf5c\ub808\uc2a4\ud14c\ub864(total-C), LDL-\ucf5c\ub808\uc2a4\ud14c\ub864(LDL-C), \uc544\ud3ec B \ub2e8\ubc31(Apo B) \ubc0f \ud2b8\ub9ac\uae00\ub9ac\uc138\ub77c\uc774\ub4dc(TG)\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0, HDL-\ucf5c\ub808\uc2a4\ud14c\ub864(HDL-C)\uc744 \uc99d\uac00\uc2dc\ud0a4\uae30 \uc704\ud55c \uc2dd\uc774\uc694\ubc95\uc758 \ubcf4\uc870\uc81c\ub85c\uc11c \uc774 \uc57d\uc744 \ud22c\uc5ec\ud55c\ub2e4. \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(HoFH) \ub3d9\ud615\uc811\ud569 \uac00\uc871\ud615 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d(HoFH) \ud658\uc790\uc758 \uc0c1\uc2b9\ub41c \ucd1d\ucf5c\ub808\uc2a4\ud14c\ub864 \ubc0f LDL-\ucf5c\ub808\uc2a4\ud14c\ub864\uc744 \uac10\uc18c\uc2dc\ud0a4\uae30 \uc704\ud55c \ub2e4\ub978 \uc9c0\uc9c8 \uc800\ud558 \uce58\ub8cc(\uc608, LDL Apheresis)\uc758 […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/organonpro.com\/ko-kr\/vytorin_ssi\/\" \/>\n<meta property=\"og:site_name\" content=\"Organon Pro - 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