{"id":9759,"date":"2025-04-14T08:06:06","date_gmt":"2025-04-14T08:06:06","guid":{"rendered":"https:\/\/organonpro.com\/en-us\/product\/tofidence\/dosing\/"},"modified":"2026-07-15T12:00:46","modified_gmt":"2026-07-15T12:00:46","slug":"dosing","status":"publish","type":"product","link":"https:\/\/organonpro.com\/en-us\/product\/tofidence\/dosing\/","title":{"rendered":"Dosing"},"content":{"rendered":"\n

Make the move. Same dosing and IV product presentation as ACTEMRA (tocilizumab)*<\/h1>\n\n\n\n

TOFIDENCE is approved for the same arthritic indications as ACTEMRA\u2014offering IL-6 receptor antagonism through weight-based dosing that supports personalized treatment<\/strong><\/h2>\n\n\n\n
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TOFIDENCE is an FDA-approved biosimilar to ACTEMRA\u2020<\/sup> based on data demonstrating they are highly similar products and have no clinically meaningful differences in safety and effectiveness.2<\/sup><\/strong><\/h3>\n\n\n\n
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*TOFIDENCE is not approved for systemic sclerosis-associated interstitial lung disease (SSc-ILD).
\u2020<\/sup>ACTEMRA is also available in a subcutaneous formulation.<\/p>\n\n\n\n

IL-6, interleukin-6; IV, intravenous.<\/p>\n\n\n\n

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Hold TOFIDENCE if a patient develops a serious infection until the infection is controlled.<\/strong><\/p>\n\n\n\n

Laboratory monitoring is recommended due to potential consequences of treatment-related laboratory changes in neutrophils, platelets, lipids, and liver function tests. Please consult the Prescribing Information for guidance on dosage modifications\/interruptions based on changes in laboratory parameters.<\/p>\n\n\n\n

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Dosing with TOFIDENCE<\/h2>\n\n\n\n
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Refer to Prescribing Information for full indications and dosing.<\/p>\n\n\n\n

\u2021<\/sup>TOFIDENCE may be used as monotherapy or concomitantly with methotrexate (MTX) or other non-biologic\nDMARDs as an intravenous infusion.<\/p>\n\n\n\n

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Dosing calculator<\/a><\/div>\n<\/div>\n\n\n\n
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