{"id":450,"date":"2022-04-14T10:31:55","date_gmt":"2022-04-14T10:31:55","guid":{"rendered":"https:\/\/vip-organon-connect-com.go-vip.net\/us\/?post_type=product&p=450"},"modified":"2025-10-06T15:22:37","modified_gmt":"2025-10-06T15:22:37","slug":"ivf-icsi","status":"publish","type":"product","link":"https:\/\/organonpro.com\/en-us\/product\/follistim-aq-cartridge\/dosing\/ivf-icsi\/","title":{"rendered":"IVF\/ICSI With FOLLISTIM AQ Cartridge"},"content":{"rendered":"\n

IVF\/ICSI With FOLLISTIM\u00ae<\/sup> AQ Cartridge (follitropin beta injection) 300 IU, 600 IU, 900 IU<\/h1>\n\n\n\n


Recommended dosing in normal ovulatory women undergoing controlled ovarian stimulation as part of an in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycle<\/h3>\n\n\n\n

The dosing scheme follows a stepwise approach and is individualized for each woman.<\/p>\n\n\n\n

    \n
  • A starting daily dose of 200 international units (IU) of FOLLISTIM AQ Cartridge is administered subcutaneously daily for at least the first 7 days of treatment.<\/li>\n\n\n\n
  • Subsequent to the first 7 days of treatment, the dose can be adjusted down or up based upon the woman\u2019s ovarian response as determined by ultrasound evaluation of follicular growth and serum estradiol levels. Dosage reductions in high responders can be considered from the sixth day of treatment onward according to individual response. The following should be considered when planning the woman\u2019s individualized dose:\n
      \n
    • For most normal-responding women, the daily starting dose can be continued until pre-ovulatory conditions are achieved (7 to 12 days).<\/li>\n\n\n\n
    • For low- or poor-responding women, the daily dose should be increased according to the ovarian response. The maximum, individualized, daily dose of FOLLISTIM AQ Cartridge is 500 international units.<\/li>\n\n\n\n
    • For high-responding women (those at particular risk of abnormal ovarian enlargement and\/or ovarian hyperstimulation syndrome [OHSS]), decrease or temporarily stop the daily dose, or discontinue the cycle according to individual response.<\/li>\n<\/ul>\n<\/li>\n\n\n\n
    • When a sufficient number of follicles of adequate size are present, dosing of FOLLISTIM AQ Cartridge is stopped and final maturation of the oocytes is induced by administering human chorionic gonadotropin (hCG) at a dose of 5,000 to 10,000 international units. The administration of hCG should be withheld in cases where the ovarian monitoring suggests an increased risk of OHSS on the last day of therapy with FOLLISTIM AQ Cartridge.<\/li>\n\n\n\n
    • Oocyte (egg) retrieval should be performed 34 to 36 hours following the administration of hCG.<\/li>\n<\/ul>\n","protected":false},"author":19,"featured_media":0,"parent":3194,"menu_order":2,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"product_categories":[],"product_specialization":[],"customer_type":[],"class_list":["post-450","product","type-product","status-publish","hentry"],"acf":[],"yoast_head":"\nIVF and ICSI Dosing With FOLLISTIM\u00ae AQ Cartridge (follitropin beta injection)<\/title>\n<meta name=\"description\" content=\"Find the recommended IVF and ICSI dosing for FOLLISTIM\u00ae AQ Cartridge (follitropin beta injection) in women with normal ovulatory cycles.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/organonpro.com\/en-us\/product\/follistim-aq-cartridge\/dosing\/ivf-icsi\/\" 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